Factors Influencing Increased Anti-Microbial Resistance and Mitigation Strategies Used Among People Living with HIV Aids Visiting Rwanda Military Hospital

Authors

  • Nadine Umutoniwase Mount Kenya University
  • Dr. Maurice B. Silali Mount Kenya University

DOI:

https://doi.org/10.53819/81018102t3107

Abstract

Antimicrobial resistance globally, regionally, and locally in Rwanda has caused hospital resistance, more-acquired infections, and increased morbidity and mortality from tuberculosis, cholera, and dysentery epidemics. Determine the prevalence of biomedical factors and mitigation strategies used against antimicrobial resistance in PLWHs, determine social cultural and beliefs influencing AMR, determine social economic and accessibility factors to comprehensive care clinic (CCC), and evaluate how KAP affects AMR and mitigation strategies in PLWHs visiting RMH. The results of this study inform the government, especially the health sector, about the main causes of anti-microbial resistance and how to mitigate them, especially in HIV/AIDS patients. Research alerts policymakers to make effective supervision of anti-microbial use to minimise drug misuse using mixed research approaches survey (quantitative) and interviews (qualitative) with descriptive study designs, purposive sampling on PLWHs, SPSS Version 27.0 data management, cross-tabulation of descriptive and inferential statistics, and pie charts. MKU School of Postgraduate Studies approved the research project, which will seek ethical clearance from MKU and RMH ethical committees to reduce AMR in Rwandan PLWHS. Antimicrobials were used by 88.2% of respondents for biomedical factors and mitigation strategies to reduce HIV/AIDS-related AMR. Social-cultural and belief factors that increase HIV/AIDS-related antimicrobial resistance Cultural beliefs or practices were reported by 62.6% of Rwanda Military Hospital visitors. Among HIV/AIDS patients visiting Rwanda Military Hospital, 73.6% cited antimicrobial cost as a factor. Lastly, KAP increased HIV/AIDS patients' antimicrobial resistance. Rwanda Military Hospital reported 62.6% unprescribed antimicrobial use. The study found that biomedical, social-cultural, socioeconomic, and knowledge-based factors increase AMR in Rwanda Military Hospital PLWHs. To optimise PLWH opportunistic infection management, the study recommended monitoring and updating treatment guidelines based on local resistance patterns.

Keywords: Anti-Microbial Resistance, Mitigation Strategies, People Living with HIV Aids, Rwanda Military Hospital

Author Biographies

Nadine Umutoniwase , Mount Kenya University

Student, Public Health, Mount Kenya University

Dr. Maurice B. Silali , Mount Kenya University

Lecturer, Public Health, Mount Kenya University

References

Ahleman, D. (2017). Cost of antimicrobial resistance: Influences on self-medication. Journal of Health Economics, 28(3), 102-110.

Berkowitz, J. (2021). The impact of antimicrobial resistance: A one health perspective. Global Health Perspectives, 15(2), 45-53.

Bonaventure, K. (2021). Social norms and antibiotic usage patterns in healthcare. International Journal of Public Health, 66(5), 543-551.

Bruno, A. (2023). Antibiotic resistance among HIV/AIDS patients: A study at Rwanda Military Hospital. African Journal of Infectious Diseases, 10(4), 231-239.

Callixte, N. (2019). Understanding antimicrobial resistance: Definitions and implications. Journal of Microbial Resistance, 22(1), 15-22.

Cecile, T. (2017). Cultural beliefs and healthcare-seeking behavior in HIV/AIDS patients. Journal of Health Behavior Research, 12(2), 67-73.

Didas, L. (2016). Socioeconomic factors and self-medication: A public health challenge. Public Health Journal, 30(3), 199-205.

Eulade, R. (2019). Self-medication practices in low-income populations and antimicrobial resistance. Journal of Pharmaceutical Sciences, 18(3), 123-130.

Fredaric, J. (2018). Education and self-medication: Impacts on antimicrobial resistance. Journal of Epidemiology and Global Health, 8(2), 85-92.

Iskandar, K., et al. (2021). Antimicrobial resistance: A global health crisis. The Lancet Infectious Diseases, 21(1), 36-38.

Kharismayekti, E. (2017). Understanding bacterial resistance mechanisms. BMC Microbiology, 17(1), 127.

Liberatore, M., & Pollack, R. (2017). Social culture and beliefs contributing to antimicrobial resistance in HIV/AIDS. Malawi Medical Journal, 29(3), 123-128.

Maina, P., et al. (2016). The influence of over-prescription on microbial resistance in Kenya. East African Medical Journal, 93(7), 475-482.

Maphalala, M., et al. (2019). Self-diagnosis and self-medication in rural populations. South African Journal of Public Health, 1(2), 85-91.

Mayer, T. (2020). Global health implications of antimicrobial resistance. Journal of Global Health, 10(1), 010401.

Mbonigaba, J., et al. (2019). Patient education and antimicrobial resistance. Rwanda Medical Journal, 76(1), 12-17.

Nugent, R., et al. (2019). WASH infrastructure and antimicrobial resistance. International Journal of Environmental Research and Public Health, 16(8), 1436.

Obeidat, H., & Aldulaimi, M. (2016). Drug abuse and antimicrobial resistance in England. Journal of Substance Abuse Treatment, 67, 24-31.

Oliver, R. (2022). Antibiotic resistance and public health: An overview. Journal of Public Health Policy, 43(2), 178-185.

Pillay, K., et al. (2017). Factors influencing antimicrobial resistance in healthcare settings. African Journal of Clinical and Experimental Microbiology, 18(1), 12-19.

Uwimana, J., et al. (2020). Healthcare access and self-medication among HIV/AIDS patients. Journal of Global Health Reports, 4, 1-9.

Wanjuk, C. (2023). Awareness of AMR and its implications in HIV/AIDS treatment. Journal of Infectious Diseases in Africa, 5(2), 45-50.

Weerakkody, N., et al. (2017). Knowledge and antibiotic resistance in HIV/AIDS patients. Cameroon Journal of Public Health, 23(1), 56-62.

Yaser, A., & associates. (2014). Poor knowledge of medication instructions and its impact on AMR in Senegal. African Journal of Pharmacy and Pharmacology, 8(34), 889-895.

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Published

2024-10-28

How to Cite

Umutoniwase , N., & Silali , M. B. (2024). Factors Influencing Increased Anti-Microbial Resistance and Mitigation Strategies Used Among People Living with HIV Aids Visiting Rwanda Military Hospital. Journal of Medicine, Nursing & Public Health, 7(2), 92–103. https://doi.org/10.53819/81018102t3107

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